Chris Vrenna is an American musician, Grammy-winning producer, engineer, remixer, songwriter, programmer, and founder of the electronic band Tweaker. Vrenna also played drums for the industrial/rock band Nine Inch Nails from 1989 until 1997. Vrenna is the current keyboardist of American rock band Marilyn Manson.

As producer, remixer, or engineer Vrenna has worked with Lords of Acid, God Lives Underwater, Megadeth, Rammstein, Metallica, The Rasmus, U2, Weezer, P.O.D., David Bowie, The Perfects, Cold, underwater, Scarling., The Smashing Pumpkins, Hole, Marilyn Manson, Rob Zombie, Green Day, Live, Adema, the Wallflowers, TheStart, and Dir en grey. He has also worked with the underground industrial group Pigface and produced songs and albums for underground girl groups TCR, Jack Off Jill, and Rasputina.

Vrenna has also worked on music for several video games, including Doom 3 (as producer with Clint Walsh), Quake 4, American McGee's Alice, Enter The Matrix, Sonic The Hedgehog, Area 51, and Need for Speed Most Wanted. In 2004 he started soundtrack work on Tabula Rasa, a massive multiplayer online game. He also helped compose the theme song to the animated series Xiaolin Showdown.